I always think of this article about how her surviving a home invasion and assault and then having a violent stalker while she was doing the Nanny led to the creation of the role of professional laughers for live studio audiences:

https://www.news.com.au/entertainment/tv/flashback/how-fran-dreschers-stalker-ordeal-forever-changed-how-sitcoms-are-made/news-story/bec34c6ea975c3c139002f6990e9234d