My lab is around 65-70W, thats Router + Switch + Server (Ryzen 3600 + 3x 3.5"HDD)

Why do you really need this ?

Why not just set up a VPS and deploy the NginxProxyManager to it together with a wireguard tunnel to your home system.

You really dont need 2 proxies…

Or if you want to keep the NPM localy on your home server, then you just setup wireguard on VPS with NAT and port forward to your tunnel.