Hyperosmolal vaginal lubricants markedly reduce epithelial barrier properties in a three-dimensional vaginal epithelium model - eviltoast
Most of the widely used vaginal lubricants in the U.S. and Europe are strongly hyperosmolal, formulated with high concentrations of glycerol, propylene glycol, polyquaternary compounds or other ingredients that make these lubricants 4 to 30 times the ...

Looking at any interesting effects of propylene glycol in vaginal lubricants I stumbled upon this study. Then I found it isn’t the only one pointing to hyperosmolal lubes causing damage to the epithelium either.