Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.
"Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised. "
Paper says
“Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells”
I love how they probably used chatgpt to summarize the article for their website. And jumping from here to saying “this vaccine is effective against everything ever” seems a bit! over reaching. Even universal vaccines within a given subtype are finicky. There seems to be a trade off between universality (of recognition) and of effectiveness. Nevertheless this seems like a different mechanism than previous RNA/protein vaccines in that it seems to work by inducing innate immunity. Even though they say that mice remain immune 90d post vaccination, that is another area where mice and men can be substantially different, so I think we are still at the wait and see stage unfortunately.
And this joke of a sentence here
"With one vaccine injection, they found the mice were protected from a lethal dose of the unmodified virus for at least 90 days. Note that some studies show nine mouse days are roughly equivalent to one human year. "
Website says
"Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised. "
Paper says
“Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells”
I love how they probably used chatgpt to summarize the article for their website. And jumping from here to saying “this vaccine is effective against everything ever” seems a bit! over reaching. Even universal vaccines within a given subtype are finicky. There seems to be a trade off between universality (of recognition) and of effectiveness. Nevertheless this seems like a different mechanism than previous RNA/protein vaccines in that it seems to work by inducing innate immunity. Even though they say that mice remain immune 90d post vaccination, that is another area where mice and men can be substantially different, so I think we are still at the wait and see stage unfortunately.
And this joke of a sentence here
"With one vaccine injection, they found the mice were protected from a lethal dose of the unmodified virus for at least 90 days. Note that some studies show nine mouse days are roughly equivalent to one human year. "
Wohooo we are immune for 10 years!!!