NAC makes you insensitive to alcohol - eviltoast

N-acetylcysteine (NAC) is a harmless (EDIT: please check at least https://en.wikipedia.org/wiki/Acetylcysteine for possible side effects) compound which protects your liver, you can buy after searching like for 10 seconds

I ve been taking it for a week (1 pill, 600mg per day) before noticing that drinking doesn’t do anything. Went to a party, drank 3 pints of beer, one after another, with absolutely zero effect. Usually, just 1 pint is enough to get socially talkative, 3 pints of beer i am supposed to be very obviously drunk.

Another time, drank a third of a bottle of wine (at my place, so it cannot possibly be watered down), the only effect was nausea (which never happened before), again, zero drunk-ness effect.

Now, depending on people that anti-alcohol protection might be an advantage or drawback. I just found it interesting, so sharing here

Edit: as one comment points out: https://pubmed.ncbi.nlm.nih.gov/30019966/

      • Eheran@lemmy.world
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        1 year ago

        This paper presents a rationale for investigating the use of N-acetyl cysteine (NAC) to promote abstinence or reduce heavy alcohol consumption for patients with an alcohol use disorder, particularly in the presence of liver disease.

        No, that is not what the article is about. It is about reduced consumption.

        • EvilHaitianEatingYourCat@lemmy.worldOP
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          1 year ago

          NAC does protect the liver, that a fact. It’s also used to treat paracetamol overdose which otherwise, would kill the liver. I don’t know how to interpret that sentence you cited

          • ClockworkOtter@lemmy.world
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            1 year ago

            It is known to protect the liver in specific circumstances, i.e. paracetamol overdoses, but there is not the same body of clinical evidence to support the same hypothesis in relation to alcohol. Even in paracetamol overdoses there is a time limit in its efficacy.

            NAC is not a panacea when it comes to drug-induced liver injury.

          • blujan@sopuli.xyz
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            1 year ago

            That sentence says clearly it is used to reduce alcohol consumption, especially in patients with liver disease. It might also protect the liver but it doesn’t say that.