As a nurse, Can someone explain to me how a person OD'ing on Fentaynol can get not one but two Narcan shots and still not come to? How much Fent do you need to use to get a tol that strong? - eviltoast

tol is Tolerance.

  • BearOfaTime@lemm.ee
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    15 days ago

    Yep, other conditions, other medications, who knows? And each person is unique.

    As I understand narcan, it more assertively binds to the same receptors as opiods like fent, effectively blocking the body’s response.

    But if it’s been long enough, the body has already reacted to enough of the first drug, so the second (narcan) can only do so much.